to NovaBioAssays
NovaBioAssays LLC is a Greater Boston-based contract research organization (CRO) specialized in providing innovative mass spectrometric (MS) solutions to facilitate drug discovery and development. We offer a full suite of mass spectrometry services for quantitative and qualitative analysis of proteins and small molecules. Our featured services include:

  • Selective reaction monitoring/multiple reaction monitoring (SRM/MRM) for quantitative measurement of endo- and xeno- small molecules, peptides, oligoneucleotides and proteins in biological matrices
  • Characterization and quantitation of complex protein molecules such as antibody-drug conjugate (ADC) and glycoproteins
  • Hydrogen deuterium exchange mass spectrometry for epitope mapping and biosimilar development

We Help Your Business Grow

the best you can do is hire us

1) We partner with our clients to discover and develop innovative medicines at an accelerated pace and with reduced costs to benefit patients worldwide; 2) We are the first choice of our clients. We offer competitive services in terms of quality, speed and cost using our world-class UPLC-MS/MS biomarker/bioanalytical expertise; and 3) We retain and reward our talented employees based on their contributions to our organization, which in turn provides a consistent and reliable experience for our clients.

Enabling Techniques

innovation, precision, accuracy

UPLC-triple quadrupole MS/MS Quantification of small molecule, peptide and protein drugs/biomarkers in biological matrices using UPLC-MRM MS.

Magnetic beads-based immunoenrichment Automated immunoenrichment using magnetic beads-based approach.

MSIA pipette tips-based immunoenrichment Automated immunoenrichment using MSIA pipette tips-based approach.

Differential dimethyl labeling Generating peptide SIL-ISs using differential dimethyl labeling for fast method development, and/or sensitivity enhancement.

Chemical derivatization Chemical derivatization enabling the measurement of non-polar, low endogenous levels of small molecule biomarkers in small sample volumes via sensitivity enhancement.

UPLC-Qtof HRMS Protein and antibody-drug conjugate characterization (intact mass measurement, peptide mass mapping, glycosylation analysis, protein identification); HDX MS for epitope mapping.